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The content posted on this Resource Center has been reviewed and approved by American Journal of Infection Control. Conflict of interest statements for the video presenters are accessible on this Webpage (see Faculty Disclosures). Posting of this educational content was supported by an educational grant from CareFusion Corporation.


The objectives of this video conference are to review the process for development of HICPAC guidelines and the rating of recommendations, to describe the extent of the problem of central-line associated bloodstream infections, to assess what's new and controversial in the recently published guideline to prevent catheter-associated bloodstream infection and compare it with the previous guideline published in 2002, and to discuss future directions and methods to implement the guideline. Upon completion of this activity, participants will be able to:

  1. Describe the development of HICPAC guidelines and the rating of the recommendations.
  2. Discuss the problem of central-line associated bloodstream infections.
  3. Identify the major recommendations of the 2011 HICPAC guideline to prevent central-line‑associated bloodstream infections and changes that have occurred since publication of the last guideline.
  4. Discuss plans for implementation of the new guideline in their work settings.



Elaine Larson, RN, PhD, FAAN, CIC
Editor, American Journal of Infection Control
Professor of Pharmaceutical and Therapeutic Research
Associate Dean for Research
School of Nursing
Professor of Epidemiology
Joseph Mailman School of Public Health
Columbia University
New York, New York


Lillian A. Burns, MT, MPH
Director, Infection Control and Epidemiology
Staten Island University Hospital Staten Island, New York

Russell N. Olmsted, MPH, CIC
2011 President, Association for Professionals in Infection Control and Epidemiology (APIC)
Epidemiologist in Infection Prevention & Control Services
St. Joseph Mercy Health System
Ann Arbor, Michigan

Robert A. Weinstein, MD
Chairman of Medicine, Cook County Health and Hospitals System
Chief Operating Officer, Ruth M. Rothstein CORE Center
The C Anderson Hedberg MD Professor of Internal Medicine, Rush Medical College


Lillian A. Burns, MT, MPH, has received honoraria for consulting and lectures from Hospira, APIC, IHI, Medline Inc., and The Clorox Company.

Elaine Larson, RN, PhD, FAAN, CIC, has no financial arrangement or affiliation with a corporate organization or a manufacturer of a product discussed in this video.

Russell N. Olmsted, MPH, CIC, is a member of Speakers Bureaus for CareFusion and Baxter Healthcare. He also has attended a Faculty Summit sponsored by Sage Products, Inc.

Robert A. Weinstein, MD, has no financial arrangement or affiliation with a corporate organization or a manufacturer of a product discussed in this video.


Fridkin S, Olmsted RN. Meaningful measure of performance: a foundation built on valid, reproducible findings from surveillance of health care-associated infections. Am J Infect Control 2011;39:87-90.

Wright MO, Hebden JN, Allen-Bridson K, Morrell GC, Horan T. Health care-associated infections studies project: case 4. Am J Infect Control 2011;39:64-5.

Rebmann T, Murphy CL. Preventing catheter-related bloodstream infections: an executive summary of the APIC elimination guide. Am J Infect Control 2010;38:846-8.

Backman LA, Melchreit R, Rodriguez R. Validation of the surveillance and reporting of central line-associated bloodstream infection data to a state health department. Am J Infect Control 2010;38:832-8.

Dixon JM, Carver RL. Daily chlorohexidine gluconate bathing with impregnated cloths results in statistically significant reduction in central line-associated bloodstream infections. Am J Infect Control 2010;38:817-21.

Niedner MF, and the 2008 National Association of Children's Hospitals and Related Institutions Pediatric Intensive Care Unit Patient Care FOCUS Group.The harder you look, the more you find: catheter-associated bloodstream infection surveillance variability. Am J Infect Control 2010;38:585-95.

Wright MO, Hebden JN, Allen-Bridson K, Morrell GC, Horan T. Healthcare-associated Infections Studies Project: an American Journal of Infection Control and National Healthcare Safety Network Data Quality Collaboration. Am J Infect Control 2010;38:416-8.

Al Raiy B, Fakih MG, Bryan-Nomides N, et al. Peripherally inserted central venous catheters in the acute care setting: a safe alternative to high-risk short-term central venous catheters. Am J Infect Control 2010;38:149-53.

Jones K, Rey J, Berriel-Cass D, Hendrich A, Saravolatz L, Fakih M. Developing a process to reduce risk of intravascular catheter-related infections and complications in the non-intensive care units [presentation #12-130]. Am J Infect Control 2010;38:e104-5.

Lorente L, Jimenez A, Martın MM, Jimenez JJ, Iribarren JL, Mora ML. Lower arterial catheter-related infection in brachial than in femoral access. Am J Infect Control 2010;38:e40-2.

Peace D. Targeting zero: a systematic approach to elimination of catheter-related bloodstream infections in a pediatric healthcare system [presentation #4-037]. Am J Infect Control 2010;38:e37.

Moore CN, Landreth R, Maschmeier C, et al. Maintained low rate of catheter-related bloodstream infections (CRBSIs) after the discontinuation of a luer-access device (LAD) at an academic medical center [presentation #4-028]. Am J Infect Control 2010;38:e30-1.

Worth LJ, Brett J, Bull AL, McBryde ES, Russo PL, Richards MJ. Impact of revising the National Nosocomial Infection Surveillance System definition for catheter-related bloodstream infection in ICU: reproducibility of the National Healthcare Safety Network case definition in an Australian cohort of infection control professionals. Am J Infect Control 2009;37:643-8.

Soothill JS, Bravery K, Ho A, Macqueen S, Collins J, Lock P. A fall in bloodstream infections followed a change to 2% chlorhexidine in 70% isopropanol for catheter connection antisepsis: a pediatric single center before/after study on a hemopoietic stem cell transplant ward. Am J Infect Control 2009;37:626-30.

Wright MO, Fisher A, John M, Reynolds K, Peterson LR, Robicsek A. The electronic medical record as a tool for infection surveillance: successful automation of device-days. Am J Infect Control 2009;37:364-70.

Honeycutt M, Curry S, Goins G, Fugitt D, Wisdom C, Marotti T, Gilliam C. Implementing a catheter-associated blood stream infection prevention bundle in the neonatal intensive care unit - will it reduce methicillin resistant staphylococcus aureus [presentation #16-183]? Am J Infect Control 2009;37:e145-6.

McCalla S, Downing-Janos T, Ellsworth K, Allinger P, Kirkpatrick K, Zaicek S. Central line-associated blood-stream infections in the ICU: the struggle to achieve and the effort to maintain zero [presentation #5-39]. Am J Infect Control 2009;37:e41.


Disclosure Statement: This journal Resource Center and publication of the journal supplement are made possible by support from CareFusion Corporation.

Statement of Peer Review: The contents of this journal Resource Center and the journal supplement have been reviewed and approved for posting/publication by American Journal of Infection Control. For participants of the roundtable discussion, disclosure statements are accessible by clicking on the Faculty Disclosures tab. For the journal supplement (accessible through this Webpage), author conflict of interest statements are published in the supplement.

Disclaimer Statement: The opinions or views expressed on this journal Resource Center are those of the presenters/authors and do not necessarily reflect the opinions and recommendations of the publisher, faculty, or supporters. There may be discussion of pharmaceutical products and/or use of products that have not been approved by the US Food and Drug Administration or other regulatory authorities outside the United States. Dosages, indication, and methods of use for compounds that are referred to by the presenters/authors may reflect their clinical experience or may be derived from the professional literature or other sources. For approved product information, consult the manufacturer's prescribing information or the applicable regulatory authority.